Programme

THURSDAY 12TH SEPTEMBER 2019
12:30 – 13:00
Registration / light refreshment
13:00 – 13:15
Opening – Zdenek Havlas, Vice-President, Czech Academy of Sciences & Radislav Sedlacek, Institute of Molecular Genetics of the Czech Academy of Sciences
Session 1 – Long-non coding RNA
(Chair: Radislav Sedlacek)
13:15 – 13:45
Eleonora Leucci, KU Leuven (invited) – “LncRNAs and beyond: uncoupling cytosolic and mitochondrial-translation as an effective anti-melanoma strategy”
13:45 – 14:15
Günter Meister, University of Regensburg (invited) – “Mechanistic insights into non-coding RNA function in metabolism and disease”
14:15 – 15:15
Poster session & Coffee break
Session 2 – Long-non coding RNA
(Chair: Radislav Sedlacek)
15:15 – 15:45
Petr Svoboda, Institute of Molecular Genetics of the Czech Academy of Sciences (invited) – “Mammalian RNAi – how long non-coding RNA become small ones”
15:45 – 16:15
Jan-Wilhelm Kornfeld, University of Sothern Denmark (invited) – “Long Noncoding RNAs in Energy Homeostasis and Metabolic Disease”
Session 3 – Short talks
(Chair: Petr Kasparek)
16:15 – 16:30
Marcela Hortova Kohoutkova, International Clinical Research Center (ICRC), Brno – “Calcineurin-NFAT alters the energy metabolism of activated human monocytes”
16:30 – 16:45
Olga Gewartowska, Institute of Biochemistry and Biophysics, Polish Academy of Sciences – “A new mouse model for Osteogenesis imperfecta reveals a link between polydenylation by TENT5A and the pathogenesis of the disease”
16:45 – 17:15
Break
17:15 – 17:30
Eliska Davidova, Institute of Biotechnology of the Czech Academy of Sciences & Faculty of Science, Charles University – “Elimination of senescent cells by mitochondrial targeting improves type 2 diabetes mellitus”
17:30 – 17:45
Tania Sorg, PHENOMIN – ICS – “Understanding the variability of the fecal microbiota and large scale evaluation of Host – Microbial genetics interactions: impact of the IMPC knock-out resource for the microbiota community”
17:45 – 18:00
Albina Rahim, British Columbia Cancer Agency & University of British Columbia – “Automated Big Data Analysis Methods and Their Applications for Cell Population Identification”
18:00 – 18:30
Asrar Ali Khan, Infrafrontier GmbH, Germany – “The INFRAFRONTIER Research Infrastructure and the European Mouse Mutant Archive (EMMA)”
Informal part
18:45
Bus transport to Pocernicky pivovar
19:30 – 22:00
Networking event – informal dinner (Pocernicky pivovar)
FRIDAY 13TH SEPTEMBER 2019
Session 4 – Metabolism
(Chair: Jan Prochazka)
09:00 – 09:30
Jan Rozman, Institute of Molecular Genetics of the Czech Academy of Sciences (invited) – “Exploiting the IMPC resource to detect new gene functions linked to human metabolic disease”
09:30 – 10:00
Thomas Werner, University of Michigan (invited) – “Mouse phenotypes are directly correlated to gene regulation – revealing MORE about promoters”
10:00 – 10:30
Raffaele Teperino, Helmholtz Zentrum München (invited) – “Epigenetic control of metabolism within and across generations”
10:30 – 11:00
Je Kyung Seong, Seoul National University (invited) – “Single cell transcriptomic analysis of beige adipogenesis in CL-treated mouse”
11:00 – 11:30
Coffee break
Session 5 – Metabolism
(Chair: Jan Rozman)
11:30 – 11:45
Marco Boscaro, DSI – Data Sciences International – “Phenotyping or distressing? Improved animal welfare and high quality data”
11:45 – 12:00
Jitka Zrostlikova, HPST – “From data to conclusions: Software workflows for metabolomic analysis”
12:00 – 12:15
Andreas Mölich, Sable Systems Europe – “13C-Glucose Oxidation Testing in Laboratory Mice: Effects of temperature, dose, and nutritional state”
Closing
12:15 – 13:00
Svante Pääbo, Max Planck Institute for Evolutionary Anthropology (keynote closing lecture) – “A Neandertal Perspective on Humans Origins”
13:00 – 13:15
Radislav Sedlacek, Institute of Molecular Genetics of the Czech Academy of Sciences – Summary & Closing
Informal part
13:15 – 14:30
Discussion & networking at poster area with light refreshment