The conference is preceded by the Fall meeting of the International Mouse Phenotyping Consortium (IMPC) on 15 – 16 September 2024.
For more information on IMPC Fall meeting, please visit:
https://www.phenogenomics.cz/2024/06/impc-fall-meeting/

Programme

TUESDAY 17TH SEPTEMBER 2024
9:00 – 9:30
Registration
Opening + Session 1 – Models to understand gene function in vivo I
(Chair: Radislav Sedláček)
9:30 – 9:45
Radislav Sedlacek, Czech Centre for Phenogenomics, Institute of Molecular Genetics of the Czech Academy of Sciences, Czech Republic
“Welcoming Lecture: CCP 2024: Leveraging the Mouse Models to Understand Gene Function and their Role in Human Diseases”
9:45 – 10:30
David Sabatini, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Czech Republic (keynote speaker)
10:30 – 10:55
Yann Herault, Institute of Genetics and Molecular and Cellular Biology, France
“Liver Disease in Down Syndrome”
10:55 -11:15
Coffee break/poster session
Session 2 – Models to understand gene function in vivo II
11:15 – 11:40
Eun Young Kim, Ajou University, School of Medicine, Republic of Korea
“Peptidyl Prolyl Isomerase Fine-tunes Circadian Rhythm”
11:40 – 12:05
Manuel Goncalves, Leiden University Medical Centre, Department of Cell and Chemical Biology, Netherlands 
“Models for Duchenne Muscular Dystrophy & Dystrophin Repair”
12:05 – 12:30
Jan Prochazka, Czech Centre for Phenogenomics, Institute of Molecular Genetics of the Czech Academy of Sciences, Czech Republic
“Ameloblastin as a General Calcium Regulator”
12:30 – 13:00
Discussion with speakers
Lunch break
13:00 -14:15
Lunch break/poster session
Session 3 – IMPC disease models & gene function
14:15 – 14:35
Mojca Bencina, National Institute of Chemistry, Slovenia
“Centre for the Technologies of Gene and Cell Therapy: Advancing Healthcare Through Synthetic Biology”
14:35 – 14:55
tba
14:55 – 15:15
tba
15:15 – 15:30
Discussion with speakers
15:30 – 16:00
Coffee break / poster session
Session 4 – Non-coding & therapy
16:00 – 16:25
Judith Zaugg, European Molecular Biology Laboratory, Germany
“Systems Epigenetics: Integrate Genetic and Non-genetic Disease Evidence for Studying Disease Mechanisms”
16:25 – 16:50
Martin Kircher, Professor of Regulatory Genomics, Institute of Human Genetics, Campus Lübeck, Germany
“Scoring Genetic Variation in Coding and Non-coding Sequences”
16:50 – 17:35
Jef D. Boeke, NYU Langone Health, United States (keynote speaker)
17:35 – 18:00
Discussion with speakers
WEDNESDAY 18TH SEPTEMBER 2024
Session 5 – Models for gene therapy & genome editing
9:00 – 9:25
Martin Jinek, University of Zurich, Department of Biochemistry, Switzerland
“CRISPR/Cas & Genome Editing”
9:25 –9:50
Hyunji Lee, KMPC and College of Medicine, Korea University, Republic of Korea
“Strategies for Creating Mitochondrial Genetic Engineering Mouse Model”
9:50 – 10:15
Pavel Krejci, Masaryk University, Faculty of Medicine, Czech Republic
“FGFR3 in Skeletogenesis and Achondroplasia: New Treatment Development”
10:15 – 10:40
Jun Won Park, KMPC and Department of Laboratory Animal Medicine, College of Veterinary Medicine, Seoul National University, Republic of Korea
“Mouse Models for Dynamics of Epithelial Cell Plasticity During Gastric Carcinogenesis and Metastasis”
10:40 – 11:00
Discussion with speakers
11:00 – 11:20
Coffee break /poster session
Session 6 – Short presentations: Selected poster presentations & technology talks
11:20 – 11:35
tba
11:35 – 11:50
tba
11:50 – 12:05
tba
12:05 – 12:20
company talk (Accela)
12:20 – 12:35
company talk (Bio-Rad)
12:35 – 12:50
company talk (tba)
12:50 – 13:10
Discussion with speakers
Lunch break
13:10 – 14:10
Lunch break / poster session
Session 7 – Rare diseases & bottom-up efforts to develop (gene) therapies
14:10 – 14:35
Kacper Lukasiewicz, Medical University of Bialystok, Psychiatry Clinic, Poland
“Insights into PACS2-related Syndrome: Lessons from In Vitro and In Vivo Models”

Piotr Kosla, PACS2 Research Foundation, Poland
14:35 – 15:00
Spela Mirosevic, CTNNB1 Foundation, Slovenia
“Finding a Cure for CTNNB1 Syndrome: The Role of the Foundation” (10 min)

Dusko Lainscek, National Institute of Chemistry, Department of Synthetic Biology and Immunology, Slovenia
“Finding a Cure for CTNNB1 Syndrome: Reserch Presentation” (15 min)
15:00 – 15:25
tba
15:25 – 15:50
Discussion with speakers
15:50 – 16:15
Coffee break/poster session
Session 8 – Closing
16:15 – 17:00
Cathleen Lutz, The Jackson Laboratory, United States (concluding keynote lecture)
“After the Diagnosis: Gene Based Therapies and the Road to Treatments”
17:00 – 17:10
Radislav Sedlacek, Czech Centre for Phenogenomics Institute of Molecular Genetics of the Czech Academy of Sciences, Czech Republic
“Closing remarks”
THURSDAY 19TH SEPTEMBER 2024
Czech-Korean Workshop on Phenogenomics – Satellite Event