THURSDAY 12th SEPTEMBER 2019
12:30 – 13:00
Registration / light refreshment
13:00 – 13:15
Opening - Zdenek Havlas, Vice-President, Czech Academy of Sciences & Radislav Sedlacek, Institute of Molecular Genetics of the CAS
Session 1 - Long-non coding RNA
(Chair: Radislav Sedlacek)
13:15 – 13:45
Eleonora Leucci, KU Leuven (invited) - "LncRNAs and beyond: uncoupling cytosolic and mitochondrial-translation as an effective anti-melanoma strategy"
13:45 – 14:15
Günter Meister, University of Regensburg (invited) - "Mechanistic insights into non-coding RNA function in metabolism and disease"
14:15 - 15:15
Poster session & Coffee break
Session 2 - Long-non coding RNA
(Chair: Radislav Sedlacek)
15:15 - 15:45
Petr Svoboda, Institute of Molecular Genetics of the CAS (invited) - "Mammalian RNAi - how long non-coding RNA become small ones"
15:45 - 16:15
Jan-Wilhelm Kornfeld, University of Sothern Denmark (invited) - "Long Noncoding RNAs in Energy Homeostasis and Metabolic Disease"
Session 3 - Short talks
(Chair: Petr Kasparek)
16:15 - 16:30
Marcela Hortova Kohoutkova, International Clinical Research Center (ICRC), Brno - "Calcineurin-NFAT alters the energy metabolism of activated human monocytes"
16:30 - 16:45
Olga Gewartowska, Institute of Biochemistry and Biophysics, Polish Academy of Sciences - "A new mouse model for Osteogenesis imperfecta reveals a link between polydenylation by TENT5A and the pathogenesis of the disease"
16:45 - 17:15
17:15 - 17:30
Eliska Davidova, Institute of Biotechnology of the CAS & Faculty of Science, Charles University - "Elimination of senescent cells by mitochondrial targeting improves type 2 diabetes mellitus"
17:30 - 17:45
Tania Sorg, PHENOMIN – ICS - "Understanding the variability of the fecal microbiota and large scale evaluation of Host – Microbial genetics interactions: impact of the IMPC knock-out resource for the microbiota community"
17:45 - 18:00
Albina Rahim, British Columbia Cancer Agency & University of British Columbia - "Automated Big Data Analysis Methods and Their Applications for Cell Population Identification"
18:00 - 18:30
Asrar Ali Khan, Infrafrontier GmbH, Germany - "The INFRAFRONTIER Research Infrastructure and the European Mouse Mutant Archive (EMMA)"
Bus transport to Pocernicky pivovar
19:30 - 22:00
Networking event - informal dinner (Pocernicky pivovar)
FRIDAY 13th SEPTEMBER 2019
Session 4 - Metabolism
(Chair: Jan Prochazka)
09:00 - 09:30
Jan Rozman, Institute of Molecular Genetics of the CAS (invited) - "Exploiting the IMPC resource to detect new gene functions linked to human metabolic disease"
09:30 - 10:00
Thomas Werner, University of Michigan (invited) - "Mouse phenotypes are directly correlated to gene regulation - revealing MORE about promoters"
10:00 - 10:30
Raffaele Teperino, Helmholtz Zentrum München (invited) - "Epigenetic control of metabolism within and across generations"
10:30 - 11:00
Je Kyung Seong, Seoul National University (invited) - "Single cell transcriptomic analysis of beige adipogenesis in CL-treated mouse"
11:00 - 11:30
Session 5 – Metabolism
(Chair: Jan Rozman)
11:30 - 11:45
Marco Boscaro, DSI - Data Sciences International - "Phenotyping or distressing? Improved animal welfare and high quality data"
11:45 - 12:00
Jitka Zrostlikova, HPST - "From data to conclusions: Software workflows for metabolomic analysis"
12:00 - 12:15
Andreas Mölich, Sable Systems Europe - "13C-Glucose Oxidation Testing in Laboratory Mice: Effects of temperature, dose, and nutritional state"
12:15 - 13:00
Svante Pääbo, Max Planck Institute for Evolutionary Anthropology (keynote closing lecture) - "A Neandertal Perspective on Humans Origins"
13:00 - 13:15
Radislav Sedlacek, Institute of Molecular Genetics of the CAS - Summary & Closing
13:15 - 14:30
Discussion & networking at poster area with light refreshment